Recommended Answer
Hello,
In this case, you need to adjust the service user also on the IIS application pool, as described in the pre deployment guide:

By default, the NETWORK_SERVICE user owns the pool, and this user seems to have no permissions to your database.
For the Scheduler, you need to set up the user in the Windows Services.
Afterward, open the Devolutions Server Console => Edit => Database => Advanced Credentials => Apply least permissions for the Runner and Scheduler account.(greyed out for the user, but it should reflect the two users you already set in the IIS and services)
Finally, perform a Stop / Start Server from the Console
Regards,
Min